Chicago Mayor Brandon Johnson is scheduled to meet Pope Leo XIV at the Vatican on Thursday afternoon at 3:30 Rome time, in what will be the first formal audience between the American-born pontiff and a sitting mayor of his hometown. The agenda, as set out by the mayor's office on Wednesday morning, focuses on immigration, restorative justice and what officials in both Chicago and Rome have characterised as a shared concern about US enforcement policy in Latin America.

Johnson plans to present the pope with a jar of giardiniera, the pickled-vegetable condiment that has become a Chicago culinary signature, and a framed photograph of the Robert F. Kennedy Bridge over the Chicago River. The mayor's office said he will thank the pontiff for his recent public advocacy, which has included open criticism of the US war in Iran, calls for a Gaza ceasefire and pointed objections to President Donald Trump's recent immigration changes.

Pope Leo, who was born in Chicago and grew up on the city's far south side before joining the Augustinians, has used several recent homilies to flag what he has called "the moral risks of a politics that treats the migrant as a problem rather than a person." His May encyclical, Magnifica Humanitas, also drew international attention for its treatment of artificial intelligence and warfare.

The visit coincides with the third anniversary of Johnson's mayoralty, which the city marked separately with a public-safety strategy rollout and a press release running through the administration's claimed accomplishments on crime reduction, infrastructure spending and housing. Mayoral spokesperson Ronnie Reese said the trip would be self-funded through the mayor's discretionary travel budget and that no formal city business would be transacted while Johnson was overseas.

Chicago has also expanded its policy stance on federal immigration enforcement under Johnson, refusing to allow city resources to be used for civil enforcement actions and instructing public-school staff to ask federal agents for warrants before allowing access to school grounds. The city has been sued by the federal government over those policies and has, so far, prevailed at the district court level.

The Vatican has not commented on the substance of the planned meeting. Senior Vatican observers note that Pope Leo has so far avoided directly endorsing the Chicago sanctuary framework, preferring to argue from broader moral principles. Johnson is expected to brief reporters from outside the Holy See after the audience on Thursday.